An
extraordinary step forward in understanding what stops the development
of one of the most common skin cancer could help to create new
treatments available to patients within the next 5 years. In
a study recently published in the journal Cancer Cell, an international
team of scientists led by Australian researchers has discovered a gene
that helps protect the body from squamous cell carcinoma (SCC) of the
skin.
The
Australian Cancer Council estimates that two in three Australians will
be diagnosed with skin cancer before 70 years to accomplish, with
squamous cell carcinoma as the most common type. Until now, the genetic basis of cancer had not been fully understood, and the only treatment option has been surgical removal.
However, experts have found that there is a protective gene that is abnormally absent in people with this carcinoma. While
researchers originally congregated on skin cancer, they saw that this
gene is also absent in SCC arising in other tissues, such as the head
and neck, frequently associated with a poor prognosis. As
a result, scientists have shown that the absence of a protective gene
in particular cancel signal that prevents skin cells continue to grow.
The
fact that we have identified this gene provides a clear direction for
the development of strategies for prevention, how to cure cancer, in the
near future. Indeed, this study suggests that certain drugs currently used in clinical trials may be effective even on this carcinoma. The same thing happens with the prevention; There are already strategies where it increases the expression of a gene to protect a fabric. In
this case, use molecules to increase the expression of this gene can
prevent the development of skin cancer, for example in the form of
sunscreen.
In conclusion, the benefits of this study may be the hand of patients in less than 5 years.
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